Molecular Modeling is the analysis of physical forces at the molecular level and the computation of resulting structures and movement. It enables to visualize molecules and molecule properties in three dimensions. To be efficient, Molecular Modeling requires dedicated softwares, powerful hardwares, expertise to choose calculation protocoles and skillful scientific knowledge to analyze data.

The foundator of Biosiris_RA has in the past and is still developing expert algorithms for the study of proteins, peptides and drugs. The actual platform, validated in more than 250 scientific publications has been applied to a large variety of biological subjects (virus fusion, kystic fibrosis protein, vaccine, apolipoproteins, ion channels, hormone receptors, CPP, drug mechanisms ....).

The algorithm platform has three molecular objects: drugs, peptides and proteins. Properties of these molecules can be analyzed into two different types of media, the cell cytoplasm and the cell membranes. The algorithm platform is designed to work with primary sequences and 3D models of structures.

Since the algorithms are home-made, they are easily up-graded if specific needs are detected.

Biosiris_RA considers that every demand is unique: for a new project, one of our consultants will quote a feasibility study to propose different approaches and to estimate their milestone schedule, pertinence and chances to success.

Molecular Modeling is optimal in preliminary steps of a project; it can save time by optimizing experimental approaches to fewer manipulations. For instance, properties of a large number of molecules can be pre-tested in silico; optimization of a molecule property can be pre-simulated in silico. Molecular modeling is also an efficient support when the mode of action of a molecule is questioned. Biological applications are numerous but all at the cell and molecule levels: cell membrane permeability, molecule stability, binding site identification.....

Biosiris_RA is very concerned by industrial secrecy. Our calculation Computers are not connected to internet and secrecy agreements are systematically signed to legally protect both parties.