Scientific Publications

Prediction of epitopes 

M. Irnaten, X. Gallet, F. Fesy, G. Péranzi, J.C. Robert, A. Thomas-Soumarmon, R. Brasseur. "Prediction of epitopes and production of monoclonal antibodies against gastric H,K-ATPase" Protein Engineering; 11(10); 1998; 949-955.

X. Gallet, N. Benhabiles, M. Lewin, R. Brasseur, A. Thomas-Soumarmon. "Prediction of the antigenic sites of the cystic fibrosis transmembrane conductance regulator protein by molecular modelling" Protein Engineering; 8(8); 1995; 829-834.

Detection of interaction sites

X. Gallet, B. Charloteaux, A. Thomas, R. Brasseur. "A fast method to predict protein interactions sites from sequences" Journal of Molecular Biology;, 302(4); 2000; 917-926.

M. Marrec-Fairley, A. Piette, X. Gallet, R. Brasseur, H. Hara, C. Fraipont, J.M. Ghuysen, M. Nguyen-Distèche. "Differential functionalities of amphiphilic peptide segments of the cell-septation penicillin-binding protein 3 of Escherichia coli" Molecular Microbiology; 37(5); 2000; 1019-1031.

Structure-activity relationships

L. Lins, A. Couvineau, C. Rouyer-Fessard, P. Nicole, JJ. Maoret, M. Benhamed, R. Brasseur, A. Thomas, M. Laburthe. "The human VPAC1 receptor : 3D model and mutagenesis of the N-terminal domain" Journal of Biological Chemistry; 276; 2001; 10153-10160.

A. Thomas, N. Benhabiles, R. Meurisse, R. Ngwabije, R. Brasseur. "PEX, Analytical tools for PDB files. II. H-Pex: non-canonical H-bonds in alpha helices" Proteins: Structure, Function and Genetics; 43; 2001; 37-44.

Peptide study

L. Lins, B. Charloteaux, C. Heinen, A. Thomas, R. Brasseur. "«De novo» design of peptides with specific lipid-binding properties" Biophysical Journal; 90; 2006; 470-479.

M. Decaffmeyer, L. Lins, B. Charloteaux, M-H. VanEyck, Annick Thomas, R. Brasseur. ”Rational design of complementary peptides to the ßAmyloid 29-42 fusion peptide: An application of PepDesign” Biochimica Biophysica Acta; 1758; 2005; 320-327.

A. Thomas, S. Deshayes, M. Decaffmeyer, M.H. Van Eyck, B. Charloteaux, Robert Brasseur. "Prediction of Peptide Structure: how far are we?" Proteins; Structure, Function and Bioinformatics; 2006; accepted.

Membrane study

Peuvot, A.Schanck, M.Deleers, R. Brasseur. "Piracetam induced changes to membrane physical properties: a combined approach by 31P NMR and conformational analysis" Biochemical Pharmacology; 50; 1995; 1129-1134.

T. Pillot, L. Lins, M. Goethals, B. Vanloo, J. Baert, J. Vandekerckhove, M. Rosseneu, R. Brasseur. "The 118-135 peptide of the human prion protein forms amyloid fibrils and induces liposome fusion" Journal of Molecular Biology; 274; 1997; 381-393.

R. Brasseur, T. Pillot, L. Lins, J. Vandekerckhove, M. Rosseneu. "Peptides in membranes: Tipping the balance of membrane stability" TIBS; 22; 1997; 167-171.

L. Lins, B. Charloteaux, A. Thomas, R. Brasseur. "Computational study of lipid-destabilising protein fragments: towards a comprehensive view of tilted peptides" Proteins: Structure, Function and Genetics; 44; 2001; 435-447.

B. Charloteaux, L. Lins, H. Moereels, R. Brasseur. "Analysis of the C-terminal membrane anchor domains of the hepatitis C virus glycoproteins E1 and E2 : Towards a topological model" Journal of Virology; 76(4); 2001; 1944-1958

O. Bouffioux, F. Basyn, R. Rezsohazy, R.Brasseur. "Structure prediction of CPPs and iterative development of novel CPPs" in "CRC handbook of Cell penetrating peptides" (2002) Ü Langel, CRC Press, Boca Raton, FL 33431, USA.

PEX

A. Thomas, O. Bouffious, D. Geeuricks, R. Brasseur. "Pex, analytical tools for PDB files. I. GF-Pex: basic file to describe a protein" Proteins: Structure, Function and Genetics; 43(1); 2001; 28-36.

A. Thomas, N. Benhabiles, R. Meurisse, R. Ngwabije, R. Brasseur. "Pex, analytical tools for PDB files. II. H-Pex: noncanonical H-bonds in alpha-helices" Proteins: Structure, Function and Genetics; 43(1); 2001; 37-44.

D. Lejeune, N. Delsaux, B. Charloteaux, A. Thomas, R. Brasseur. "Protein-nucleic acid recognition: Statistical analysis of atomic interactions and influence of DNA structure" test Proteins: Structure, Function and Bioinformatics; 61(2); 2005; 258-271.